I've been revisiting anno 2205, infamously the ugly duckling of the Anno series of RTS games. I don't mind so much the fact that it's different, lacks customisation and random map generation - I'm bothered because the game is so slow to progress through on challenge settings, and it feels like a game designed just to artificially waste your time; in other anno games, you can always pull tricks to dig yourself out of economic crisis - selling off assets and surplus goods, completing quests for other parties, or taking loans. 2205 is very very confined in terms of what you can do to financially recover in the early game and forces you into a lot of military events.
I have a Logitech g502, so I have 2 extra buttons next to m1 and 3 on the side. Quick melee is always on a side button as well lol. Holding middle mouse to aim grenades always feels awkward to me because of the roll, and that’s always been my first switch to fail on pretty much every mouse I’ve ever owned. I honestly think it’s the single worst physical key to bind an action to in a video game from a tactile perspective.
In super fast paced fps shooters I usually use G, but that’s just because of muscle memory going back to like Half-Life 1/CS1.6. I tried swapping to a side button for my grenades in the finals and it was not viable for me at all lol.