this post was submitted on 27 Apr 2024
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No Stupid Questions

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I know that DNA encodes proteins. Truthfully, everything besides that (including 'what are proteins') mostly wooshes over my head, but that's not relevant because whenever I search this question I never even find it addressed anywhere.

The human body has, among other things, two hands each with five fingers, with a very particular bone structure. How are things like that encoded in DNA, and by what mechanisms does that DNA cause these features to be built the way they are? What makes two people have a different nose shape? Nearly everyone in my family has a mole on the left side of their face, how does that come about from DNA?

I'm sure there are many steps involved, but I don't see how we go from creating proteins to reproducibly building a full organism with all the organs in the right places and the right shapes. Whenever I try to look this up, all of these intermediate steps are missing, so it basically seems like magic.

As I said, any explanation will most likely go over my head and I won't be able to understand it fully, but I at least want to see an explanation. I'll do my best to understand it of course.

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[โ€“] phdepressed@sh.itjust.works 5 points 6 months ago (1 children)

No, and no. My PhD thesis was on gene delivery. We're barely getting into the simplest modifications for disease treatment. Multigene stuff, and spatiotemporal control is still a ways off.

I would say sort of. They could do it, but the result wouldn't survive very long. Probably not even to birth.