god damn the comments on this post are the fucking wild west
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... in mice.
Finally! Finally they're trying to take the bullets out of the gun instead of trying to make a stronger bulletproof vest. I feel cautiously optimistic!
I'm a bit jealous that there's no side effects, though. Depo made me gain 30lbs in ONE month. I'm lucky it made my tits significantly bigger (Went from a B to a DD), but that was not a fun experience.
She would still have to either trust him or take birth control herself as well.
Safe, cheap, permanent but trivially reversible male birth control was invented in 1979 and has yet to be approved for US sale.
I can't find much on the mechanism of action (serine/threonine kinase antagonism), other than it's been tried to fight cancer and failed, hopefully it doesn't have any terrible side effects.
It sounds safer than the retinoic acid antagonist one that was posted a while ago anyway, I can't imagine a drug that does the opposite of tretinoin will be popular.