Not often, but those "agree to extra terms to continue viewing the content that you were already looking at for 0.9 seconds" pop-ups (cookie walls and the like) sometimes pop the agree button exactly under where I'm clicking, or activate the button with spacebar that I was just using to scroll down a page
Always wonder if it is a valid legal defense if the pop-up can be dismissed faster than it is possible to read them, but I'm afraid of the potential global consequences if I were to challenge that