I found the easiest to work with to be QT.
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Qt no doubt.
Cute
QT + KFramework. SDL2 for games.
Qt by a country mile. Wayland is just another backend, and you won't notice a difference between targeting Wayland and any other platform -- unless you're doing platform specific things in your app (like tray icons, but even then...)
Electron 😎✨️
Settle down, Satan.
FIREFOX!
There used to be a Mozilla alternative, and then it got discontinued. :(
I've played around with (only played around with, I haven't done any actual development with either but I've heard they're similar) GTK, QT and Tk (actually tkinter from Python), and QT seems the most intuitive. It just feels right to me, compared to the others.