How bizarre! Usually when I'm having a bad night, sleep helps me because the thoughts quiet down. I've been on a low dose of Seroquel. Bad thoughts can get to me at night but I seem to just fall asleep on the med which makes them go away and stay quiet into the next morning!
this post was submitted on 08 Mar 2026
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Mental Health
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I actually take my antidepressants right before I go to bed, and they seem to last the next day.
I do get really upsetti if I stay up later than usual, and am generally lower in mood at night. But that could be a number of things.
Seems common enough to have a lower mood at night. Idk why really but I've always been the same.
If you need Duloxetine in order to sleep, then I don't know... Otherwise, I do this: I take Sertraline in the morning when I wake up and it last the whole day. Then, when I need to sleep - and if I'm unable to sleep because kdw anxiety - I take Zoplicone, which knocks me out. It's not an antidepressant nor is it ani anxiety medicine, it just induces sleep.
No but I usually get real high after I wake up. Before I go to sleep as well.