if you have a pixel theres absolutely no reason why you shouldnt use it.
Plenty reasons to not use it on a pixel...I had horrible compatibility with all sorts of banking apps, government 2FA and traffic warning systems, to the point where they just couldn't work at all. Their sandboxed play services breaks a shitload of day to day convenience and even necessities to increase privacy.
Yes, they're a nuisance to carry around anyway.