this post was submitted on 12 Sep 2026
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Ah yes, Brain damage in a canister.
Only if used very irresponsibly. You can inhale 500 of those canisters in a night, just make sure to breathe air between hits and take a break of a few weeks afterwards, let your B12 regenerate and youre good. Probably less harmful than a bottle of wine. Luckily the war on drugs gave us extensive education to avoid such silly mistakes and handle drugs with care. /s
Edit: So this comment sounded too carefree Ill admit. Obviously dont do 500 canisters of nitrous in a day, you will probably regret it. I was exaggerating. Even if true in theory, it is not likely that you can do that much while following safety guidelines.
Im saying it is safe to use only when doing it correctly. Using a balloon, lying down(never standing), breathing between doses and taking long breaks (~ a month) between sessions are a must, but easily doable. If possible, have someone with you. Supplementing B12 a few days after sessions is also advisable.
if you tell yourself that to feel yourself more safe I'm not gonna break the spell.
But damn I was waiting to see what kind of comment addicts would leave.
500 canisters darn it!
like only thinking about the money people may spend to get high instead of using it for literally whatever else.
The user you're replying to is doing a public service. People are going to do drugs. People, in general, are attracted to transporting experiences. For many, that is going to include one or more substances.
Imagine half of all people didn't know it's a good idea to wear a seatbelt or wear a helmet on the bike. That's where we're at in our society in terms of educative harm reduction with drugs, even the legal ones.
Taking a moralizing stance against recreational drug usage in 2026 is just wild. It's some reefer madness shit, really counterproductive. I would examine why you feel so strongly about what someone else puts into their own body, and I mean that sincerely.
I would understand it if it said "it's not safe but doing X and Y lowers the risk" but he is basically saying that it IS safe if you do X and Y, and that's simply a whole world of difference.
I mean, barring the canister falling on your head, external factors like a plane crashing into your house, and maybe extremely rare genetic abnormalities, you will be safe if you follow those instructions to the letter and are already in good health. It's pharmacology and common sense, not magic. If it still freaks you out, that's fine - you don't need to shit on someone else's thing though, just keep yourself away from it if you already know it's not for you.
Safe as in as safe as how people used to say weed was, that it was basically inocuous, that you couldn't become addicted, yadayada until science came with evidence that yes, you can become addicted and that it also causes cognitive damage long term?
I just see again this same story of a magical drug that supposedly is totally safe if you ask people who consume it yet there are lots and lot of cases of people who caused themselves brain damage with this, suuure maybe they weren't doing your special formula, but how are you really sure about it lol.
people who say it's safe are no doctors, actually doctors I can find on the internet say it's by far a terrible idea, they are users who may have an incentive to tell themselves it's ok.
Ok now this is an interesting comparison you bring up, let's see:
Nitrous Oxide:
N~2~O, that's it, a simple molecule. It's used constantly in medical contexts, where its safety profile is so well understood and its action is so consistent, it's given to pregnant women in childbirth to manage pain and anxiety. Binds to one receptor, clear mechanism of action. Possibly the most well-understood mind-altering substance in existence.
Cannabis:
a plant - a complex multicellular organism. Consumers inhale/digest/absorb an entourage of dozens of different compounds bundled together. Countless strains, cultivars and growing methods, with no two being the same, all with their own unique genetics and chemical "fingerprint". Preparation and consumption method adds even more complexity. Multiply that by 100s of millions of consumers worldwide, each one with their own human body, no two the same. An unfathomable level of complexity, which science is actively researching on a continual basis. Binds to many different receptors/systems when consumed.
We continue ironing out the details of long term safety and how best to harness it medically. And, guess what, responsible users are more than willing to change their mind and their habits when new information is uncovered. And yet, it is still mostly safe for most people, and still safer than most other recreational substances by a wide margin. There is no practical LD50 for cannabis or its constituents. The "lethal dose" would be so comically large, it would be physically impossible to consume in time to do any harm at all. You're orders of magnitude more likely to be crushed to death by a giant weed bale accidentally falling over on top of you than you would be consuming it.
I dont know what youre on about. I dont even use Nitrous Oxide regularly, like a short session every half year or so. Im simply trying to educate people with unbased prejudices about the actual harms instead of fearmongering. A single canister is just as harmful (assuming other basic safety precautions like a balloon, lying down, breathing enough air) as 500 at a time, thats what I was trying to convey (one canister like the ones in the picture is a single dose as in a single breath which will get you sedated for about a minute, for those who dont know) I dont know if its even realistic to use so many in a single day. That would be hours of constant use.
The point Im trying to make is 1 canister on monday and 1 canister on friday is way worse for long term damages to the body than 500 on monday with a break afterwards. Its important to know for people who want to try it because its counterintuitive and differs from other drugs in that regard. Just going in uneducated like "Im not even doing that much, just once every few days" is actually harmful and easily avoidable.
Also, why judge what people spend their money on to have fun? Are you only spending it for ending wars and feeding the hungry? I assume you dont have a TV, a PC, novels, candy, fun with friends, coz those are all just hedonistic and you should judge them the same way. Oh and obviously you dont drink or smoke, right? Because society evolving in a way that made us embrace two of the most harmful drugs ever known, keeping them legal and socially accepted, does not make them less harmful. Caffeine and chocolate (theobromine) are also drugs with worse effects (even if neglectable compared to most other drugs) on the body than N2O btw. Judging people for using one drug and not for using an other would just be double standard.
If you think Nitrous Oxide has unavoidable risks, you are free to do your research and provide some sources. I will gladly be proven wrong by scientific research.
Edit: rereading my comment above, it really does sound too positive in favor of N2O, I will editi it. I dont want people to underestimate the substance either.