science

Not really if you look into the literature. There were several studies done at Stanford and several hundred thousand people that took it for fat loss and less than 100 deaths from what I've seen. Also, a majority of those deaths were from suicide, which is both a sad thing and a terrible way to go. The deadly dose was about 5-6x the normal dose. There was a case of a girl ODing on it to get ready for spring break and I believe she was around 10x the standard dose. Note dosage is based off body weight.

Now there are other issues that can occur because of the MoA it causes you to burn through zinc and magnesium. There are thyroid issues that can occur, as well as the possibility of cataractics. Then there's the proton slip and electron leakage within the mitochondria. This is what causes a majority of the problems as it's a positive feedback loop for negative cascades. That can be almost entirely negated by keeping dose lower and doing your cardio. It can be done safely if you know what you're doing but most people aren't that reasonable.

Someone wrote an interesting book on it and took more of a conspiracy standpoint on it claiming it could be effective fat loss but because it was cheap and easy it would cut into big pharma making money. Can't say I agree with everything in the book but there was some useful information.

There's also a newer compound called BAM-15. In research it's more effective at fat loss and can be taken at much higher doses safely. I believe they got up to 20x the dnp standard dose without negative side effects in the lab rats.