I have already personally defederated from the likes of hexbear.net (my prior instance had not done that) and lemmy.ml - the latter I even switched instances specifically to be able to do (although now that I'm here I'm finding it amazing what features are here that Lemmy lacks, like Categories on top of Communities).

There is a difference between a valid point of view, presented in good faith, vs... the opposite of that, masquerading itself as a merely "different POV". In essence, while I am aware that I blocked many good people and therefore some good content, I decided that it was a good trade-off for me to be able to halt the flood of what is essentially spam sent out to the Fediverse from those instances.

I would rather see receipt of such spam be opt-in rather than have to find a way to opt-out, but it is what it is. At which point yes, according to this perspective at least, under this set of value judgements, then it is helpful that so many of the spammers congregate into one place making that process easier. At the expense of others who are now blocked as well, having done or even intended no wrong but being caught up in that war of ideologies. We live in a society though and our actions impact others, whether we like or even acknowledge that or not.