this post was submitted on 07 Jun 2025
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Science Memes

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submitted 1 day ago by fossilesque@mander.xyz to c/science_memes@mander.xyz
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[–] kautau@lemmy.world 11 points 20 hours ago (1 children)

Maybe at some point we'll have version control for all DNA mapping so each minor change is a commit hash and each major release is a tag

[–] tetris11@lemmy.ml 4 points 13 hours ago* (last edited 13 hours ago) (1 children)

We do, the major versions have tag releases like mm7, mm8, mm9, etc. as defined by the current build, and minor patch releases too like mm10p14 as new sequences come in.

https://hgdownload.cse.ucsc.edu/goldenpath/mm10/bigZips/

Example, say you have 5 sequences: CAT, ATC, ATCG, CGT, and ATATA.

One way of combining them up together to build a transcriptome is like this:

5 sequences:     ATATA
               CG-T  ATC
             ATCG CAT

  Reference: ATCGATATATC

ATCGATATATC isn't the only solution to these sequences, but as you get more sequences to try and overlap, the more the uncertainty goes down

[–] kautau@lemmy.world 2 points 7 hours ago

That’s really interesting, thanks for sharing