this post was submitted on 15 Nov 2023
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[–] EntropyNZ@alien.top 1 points 10 months ago

Tramadol is a weird one. It is an opioid, but it's also an SNRI (serotonin-norepinephrine reuptake inhibitor). It's actually not really safe to be taking with something like a TCA because of that (risk of Seratonin syndrome).

They're still prescribed together quite often, despite that.