CNN: Why has HPV vaccination historically been emphasized more for girls and women?

Wen: The initial focus of the HPV vaccine was driven by the clear and direct link between HPV and cervical cancer, which is a major global health issue. According to the World Health Organization, cervical cancer is the fourth most common cancer in women globally, causing more than 660,000 new cases and around 350,000 deaths in 2022.

Early clinical trials and public health campaigns prioritized preventing this specific cancer, so vaccination programs were first rolled out for girls. Over time, as more evidence accumulated about the burden of HPV-related disease in men, recommendations have expanded to include boys. However, public perception has lagged behind the science, and many people still think of this vaccine as primarily targeted for females.