#FT: Viktoria Plzen 1-0 Dinamo Zagreb
Plzen scorers: Tomas Chory (Pen 34')
Zagreb scorers:
Venue: Doosan Arena, Plzen
#FT: Besiktas 1-2 Bodø/Glimt
Besiktas scorers: Tayfur Bingöl (64')
Bodø/Glimt scorers: Faris Moumbagna (38', 49')
Venue: Tüpraş Stadyumu, Istanbul
#FT: Legia Warszawa 2-0 Zrinjski Mostar
Legia scorers: Rafal Augustyniak (14'), Josué (Pen 30')
Mostar scorers:
Venue: Stadion Miejski, Warsaw
#FT: Cukaricki 0-1 Fiorentina
Cukaricki scorers:
Fiorentina scorers: M'Bala Nzola (Pen 6')
Venue: Gradski Stadion Dubočica, Leskovac
#FT: Ferencvaros 1-1 Genk
Ferencvaros scorers: Aleksandar Pesic (48')
Genk scorers: Daniel Munoz (62')
Venue: Groupama Arena, Budapest
#FT: HJK 0-1 Eintracht Frankfurt
HJK scorers:
Frankfurt scorers: Fares Chaibi (31')
Venue: Bolt Arena, Helsinki
#FT: PAOK Thessaloniki 2-2 Aberdeen
PAOK scorers: Taison (23'), Mbwana Samatta (67')
Aberdeen scorers: Duk (14'), Jamie McGrath (70')
Venue: Stadio Toumbas, Thessaloniki
#FT: Nordsjælland 1-1 Spartak Trnava
Nordsjælland scorers: Marcus Ingvartsen (32')
Trnava scorers: Michal Duris (64')
Venue: Right to Dream Park, Farum