It's a cool feature, and I played with it some, but I don't really see how to use it in a home or small office environment unless you're willing to subscribe to someone who can generate the live patches for you.
I can certainly generate the patches myself, but it's much faster to let the maintainer of my distro's kernel handle shipping new packages and accepting the reboot. My system reboots really quickly.
If high reliability is a concern, I would suggest load balancing or some other horizontally scaled solution such that you're not impacted by one machine going down. Because they will go down for things other than updates!