Th4tGuyII

joined 2 years ago
[–] Th4tGuyII@kbin.social 2 points 1 year ago

Pretty much...

Recessive malfunctions can hide away amongst carriers for generations before manifesting any deformities, during which time they have no effect on the carrier's survival, so there's very little selective pressure against them.

Dominant malfunctions which cause deformities simply can't hide away, so have enormous selective pressure against them.

Interestingly enough though, there are times where dominant malfunctions can survive that pressure...
For example, having Sickle cell disorder increases your resistance to Malaria, so even though the full form is rarely passed on, the single allele form (which caused partial disorder) is passed on due to a slight positive selection pressure.

[–] Th4tGuyII@kbin.social 36 points 1 year ago* (last edited 1 year ago) (3 children)

I'll try to keep it relatively simple - your cells contain chromosomes that contain your genes. You usually* have two sets of every chromosome.

These genes come in different variations/mutant forms called alleles. Most alleles function more or less the same, but some malfunctions result in deformities.

If a malfunctioning allele results in errant gene inactivation, it is known as recessive, which means as long as your other copy works, you're all good.

If a malfunctioning allele results in an errant gene activation, it is known as dominant, which means if you have the allele you get the deformity regardless of if your other copy works or not.

Fortunately for life, most malfunctioning alleles are recessive, so as long as you've got high genetic variance (a lot of alleles) in a population, the chance of two people meeting with the same recessive malfunction is low.

Incest can result in a drastic decrease in genetic variation, which can result in malfunctioning alleles becoming much more prevalent than they usually would be, resulting in many more cases of recessive deformities than in the wider population.


*For males this is not true of their sex chromosomes. Many genes present on the X chromosome are missing on the Y chromosome, which can lead to sex exclusive traits and diseases.

For example, it is the reason why there are almost no calico/tri-colour male cats, as the genes for it are in X but not Y chromosomes.

[–] Th4tGuyII@kbin.social 3 points 1 year ago

Exactly. In a sane world, cops shouldn't ever be the ones escalating any situation, especially one where there is no on-going threat

[–] Th4tGuyII@kbin.social 19 points 1 year ago* (last edited 1 year ago) (2 children)

For a petty theft committed by a mentally disabled minor?

The situation was non-violent and under control - the cops escalated far beyond what was needed because they got bored waiting for the kid to fork over the last couple of e-cigarettes. There was no need to pin the kid to the ground, and definitely no need to inject them with ketamine.

In a world where all cops weren't bastards, they would have continued to build a rapport until they could convince the kid to give them back, give the kid a lecture about stealing, then let everyone be on their way.

[–] Th4tGuyII@kbin.social 1 points 1 year ago

She absolutely should - the amount of people he's stiffed that can't afford to go after him, it'd put a hole in his wallet he'd never forget if they all came knocking

[–] Th4tGuyII@kbin.social 13 points 1 year ago

What a world we live in, where charities have to step in to stop children going into debt over school lunches...

You'd think that one of the wealthiest governments in the world would have a better solution to this problem by now than relying on charity

[–] Th4tGuyII@kbin.social 15 points 2 years ago (23 children)

Yeah - that was my worry.

Unification of standards only works if everyone agrees to use it and only it (i.e. mobile phones and USB C), otherwise you're just adding another one to the pile.

[–] Th4tGuyII@kbin.social 2 points 2 years ago

Well the idea is that you're paying for someone who is both qualified in dealing with mental health issues, and is completely unattached to your life to provide a confidential, non-judgmemtal outsider perspective on your life.

The people who know you almost certainly can't provide that level of support in your life, and many people need that space/perspective to help them recognise their issues, or push them towards the correct solution to resolving them.

It's not everybody's cup of tea, it ain't mine, but for those it does work for, it works well

[–] Th4tGuyII@kbin.social 9 points 2 years ago

I know right, but apparently it's "too unsanitary" and "nobody wants blood all over their documents". Honestly, what has this world come to

[–] Th4tGuyII@kbin.social 7 points 2 years ago (2 children)

Unless I can take my blood samples home with me, it appears I'll be left behind in that trend

[–] Th4tGuyII@kbin.social 4 points 2 years ago

It's one thing to dig at your friends, you know where their boundaries are, or at least you should - but for them to so brazenly mock a complete stranger is just horrid. They don't know what you're going through, your struggles - I wonder how they'd feel about it in your shoes? It's a shame we can't make people wear ours just to see what it's like.

[–] Th4tGuyII@kbin.social 7 points 2 years ago

If you want to see your "Karma" Kbin natively has a reputation feature - Having said that I disagree with the idea entirely.

It isn't a good way to gauge trustworthiness as it can easily be farmed by posting large amounts of mediocre content that people are likely just to upvote passively.

It's far better to just look at someone's post history to see the substance of their contributions to the site - obviously that takes more work to check, but it's also way harder to fake.

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