For me it went downhill fast when they started to do "political hot topic of the week/month/year" instead of random humour with occasional current day events. Mr Garrison as Trump and similar stuff was just stupid and unfunny. Also I hate Tegridy farms...
Best South Park episodes were stuff like Scott Tenorman or Casa Bonita or the superhero or ninja episodes...
I just finished watching She-Ra, and I loved the gay characters because being gay wasn't their personality, but they were, in fact, complex, interesting characters that happened to be gay. Owl House is definitely on my list of shows to watch in the future.