I'm not an HVAC technician so I wouldn't know exactly, but I think there's two things to consider: static pressure and duty cycle. Static pressure is the fan working hard to spin which causes wear on bearings. Duty cycle is how long the machine runs. If your duty cycle is too low then the machine is turning on and off quickly which is bad.
You could look at the size of the unit and there's some rules of thumb that translate size, climate, and square footage of just the areas you leave the vent open and there are online calculators you can use.
I think the only way to know for sure is to measure the pressure drop across the intake and outflow and see what the fan motor is rated for.
Just think of all the countries and companies that grab this data, group by email address, then start to identify preferences of people around the world. Its not just for identity theft. The possibilities are endless! And horrifying.