fullsquare

joined 3 weeks ago
[–] fullsquare@awful.systems 20 points 1 week ago (10 children)

in this house we obey laws of physics

[–] fullsquare@awful.systems 18 points 1 week ago

decisive belarusian cultural victory

[–] fullsquare@awful.systems 2 points 1 week ago (1 children)

yes, these are not onions either

[–] fullsquare@awful.systems 1 points 1 week ago

it's not if you pay up https://www.wheresyoured.at/wheres-the-money/

ed paid, and that's what he got. this all comes with caveat that this count doesn't include deepseek chinese customers, but that's barely relevant to sv bubble

[–] fullsquare@awful.systems 2 points 1 week ago* (last edited 1 week ago)

claude has something like 1/30 of chatgpt userbase, it's not relevant and anthropic can't pick up opeai users when (not if) it collapses. also somehow they are even faster at burning their money

[–] fullsquare@awful.systems 2 points 1 week ago* (last edited 1 week ago) (2 children)

all your favourite boutique ocean-boiling nonsense generators combined, compared to openai products, have something like fifth of their userbase on mobile app and something like 2/3 on website. without counting deepseek (data from february - it was very fresh back then), it's closer to eigth on app and third on website

[–] fullsquare@awful.systems 32 points 2 weeks ago (1 children)

musk and thiel narrowly avoided death in 2000 car crash. can you imagine what could have been?

[–] fullsquare@awful.systems 4 points 3 weeks ago

on reddit, the website plays you

[–] fullsquare@awful.systems 13 points 3 weeks ago (4 children)

have rules never clearly explained, get banned pretty much immediately. a taste of real reddit experience™ even that i've never got banned sitewide (only on r/conservative) i guess you win if you touch grass or quit

[–] fullsquare@awful.systems 36 points 3 weeks ago (1 children)

death of millions for profit - solid business practice, congratulations and see you again at next shareholder meeting

[–] fullsquare@awful.systems 3 points 3 weeks ago

I'm with the old man on this one. Antibodies can clear out amyloid and still it has no effect on progression of disease, amyloid secretion can be blocked upstream (like with small molecule protease inhibitors) and it still has no effect. Maybe this one hits something off-target, or maybe that effect is not even real, or maybe it's some sort of statistical artifact. You'd stumble upon some false positive after trying so many times.

Aducanumab is dead in the water, trials shown no effect and it was abandoned by Biogen. This one is about lecanemab. Both have massive problems with brain edema and microhemorrages, which probably means these are not suitable for actual use. But don't worry, they already have received their reward - FDA wanted to have something, anything to show up for Alzheimer and Biogen cashed in when stock price went up

think cold fusion, or EmDrive, or string theory

That's a weird set - cold fusion or EmDrive can be tested and their physical principles are falsifiable - and they were - but string theory is different, because it's not falsifiable.

If it’s marginally but truly effective,

That if makes some mighty heavy lifting here. I think that amyloid hypothesis is closer to cold fusion than to string theory in that it had already a couple of fatal experimental refutations thrown at it, but people still shove effort this way because there's nothing else/copium/sunk cost combination

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