2800 sqft is nothing for real deal Bitcoin mining and be prepared to spend way more than 100k for a mining fleet.
If you had the knowledge and means to set up a 3D printing shop for a under-served niche you could make bank, but I think your space is more so for someone who is already running something and wants to scale.
There's honestly endless opportunities given your circumstances and capital, just do something that you think you'll find interesting and enjoyable.
Me personally though, I would either start a VR arcade or make a porn set and see who answers the ads to audition ;)
Weed gives me access to a heightened state of creativity that is just locked away without it and I've had many moments when high where I think of a great idea, but usually I'll read it sober and realize it wasn't that great. I also remember hearing if you have a mystical experience on mushrooms/LSD your Big 5 trait Openness could increase by a standard deviation which would invariably increase your baseline creativity