My setup is: Namesilo for domains, Hetzner VPS with autobackup, Mailcow selfhosted. (Few manual updates with backups per year). Just copy paste steps from Obsidian notes. Cloudflare DNS just in case of ddos etc.
I have 3 domains with maybe 6 emails and catch em all. I do not send/receive a lot. Maybe 5-10 emails per day. Most of them are notifications from systems.
All good. I'm happy.
Try Nextcloud-AIO and install the Preview Generator as well. (note that you will need to run it manually the first time). I did struggle as well, before I found the AIO. Now I'm happy. :-)