data in both animal models and humans suggest that the effects of artificial sweeteners may contribute to metabolic syndrome and the obesity epidemic. Artificial sweeteners appear to change the host microbiome, lead to decreased satiety, and alter glucose homeostasis, and are associated with increased caloric consumption and weight gain. Artificial sweeteners are marketed as a healthy alternative to sugar and as a tool for weight loss. Data however suggests that the intended effects do not correlate with what is seen in clinical practice.

https://pubmed.ncbi.nlm.nih.gov/29159583/

[–] masterofn001@lemmy.ca 11 points 5 days ago

This has been the assumption for some time now.

Body thinks it get sugar. Body produces enzymes, hormones, chemicals, etc to process sugar. No sugar or calories to metabolize. Body hungry.