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The fat storage cells definitely play a role as well. One of the ways in which the mechanism I discussed works is via leptin, as leptons regulate energy expenditure. Leptin is primarily produced by adipocytes. So, I believe that is where the connection is. This paper says some interesting stuff about it: https://doi.org/10.1242/dmm.008698.
The issue that I was discussing is that most people do not succeed with keeping the weight off. Most obese people do not manage to lose significant weight in the long term as they tend to regain the weight. We need to look at why that is to solve it. The research on setpoints offers at least a partial explanation. However, if you know about research that further explains this, I would be very interested. (Some sources if you are interested: https://pubmed.ncbi.nlm.nih.gov/17469900/, https://pubmed.ncbi.nlm.nih.gov/11684524/, https://pubmed.ncbi.nlm.nih.gov/19175510/)