much like urushiol oil from the poison ivy family, you get sensitized overtime from it. the more potent species is oak and sumac. with chemicals i think you can get sensitized over it. im guessing people who have atopic dermatitis might be very prone to this.

if you are having allergy test, you can ask to test your IGE levels, ige are high when you have chronic allergies. at a certain level like over 1000+ on the results you start to get things like ashtma, severe atopic dermatitis, and allergic rhinitis, >2000 indicates a rare disorder.