this post was submitted on 17 Feb 2026
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[–] village604@adultswim.fan 66 points 2 months ago* (last edited 2 months ago) (3 children)

But for real, don't mix the two. It's a great way to end up dead or seriously injured. I had a friend who passed out from the combo in front of a space heater and had burns on his shin that exposed bone.

Also, there's basically a hard limit on how high you can get with benzos. After a certain point you're just throwing away money.

Also also, snorting Vyvanse is wasting money. It has to go through stomach acid to work, so it has to drip out of your sinuses first.

[–] Kanda@reddthat.com 3 points 2 months ago (1 children)

It's okay if you do it responsibly (no mixing is responsible)

[–] tomi000@lemmy.world 4 points 2 months ago* (last edited 2 months ago) (2 children)

(no mixing is responsible)

What about weed + caffeine?
Alcohol + nicotine?
LSD + MDMA?
Psilocybin + nitrous?
There are a lot of combinations that are extremely safe in regular doses.
https://wiki.tripsit.me/wiki/Drug_combinations

[–] Fuck_u_spez_@sh.itjust.works 3 points 2 months ago* (last edited 2 months ago)

Caffeine and weed in combination are tragically underrated.

[–] Kanda@reddthat.com 2 points 2 months ago (1 children)

In the oop alcohol and benzos were mentioned, so I was referring to that. Apologies if the language was insufficiently specific.

[–] tomi000@lemmy.world 1 points 2 months ago

Oh I see, sorry then. Yeah those two are no good together^^

[–] Wav_function@lemmy.world 2 points 2 months ago

I'm not supporting snorting Vyvanse, but that's not how it works.

Lisdexamfetamine is an inactive prodrug that is converted in the body to dextroamphetamine, a pharmacologically active compound that is responsible for the drug's activity.[113] After oral ingestion, lisdexamfetamine is broken down by enzymes in red blood cells to form L-lysine, a naturally occurring essential amino acid, and dextroamphetamine.[6] The half-life of this conversion is roughly 1 hour. The conversion of lisdexamfetamine to dextroamphetamine is not affected by gastrointestinal pH and is unlikely to be affected by alterations in normal gastrointestinal transit times.

Enzymes in your blood convert it to dextroamphetamine, has nothing to do with stomach acid.

https://en.wikipedia.org/wiki/Lisdexamfetamine