DiMarchi and Tschöp's pioneering work on the study of GLP-1 hormones contributed to the foundation for popular weight-management drugs sold under name brands like Zepbound and Wegovy. They discovered that the weight-loss effects from therapeutics containing the GLP-1 hormone activity could be enhanced by including two other hormone activities: glucagon and GIP.

Not this time, right now we're talking about other drugs that can be used for weight loss.

eating less?

Eating less calories?

Yes.

Eating less volume/weight?

Weirdly, no.

The reason people keep fucking it up, is they try to maintain an empty stomach, working against evolutionary instincts as old as we've had stomachs.

What you do, is eat bulky foods that take a long time to digest. That keeps your stomach "happy" instead of sending signals to eat more, it just digests what it has. Over time your stomach stops expanding as much when eating and you can't eat as much in one sitting. And your gut biome changes which kills sugar cravings so many people struggle with. Adding up to a slip and binge going from disasterous to just not even noticable.

You can still eat ice cream and junk food too, you just won't want to eat much, and you physically cant eat much because you're literally full of salad.

The only problem is, there's absolutely zero money in getting people to eat salads.

There's a shit ton of money in semiglutides, especially since if people stop they gain the weight back in like 2 years

Wait, can we do this?

Go back to Russia, you communist.