this post was submitted on 23 Jun 2026
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In an extremely odd case, a single 79-year-old patient was granted early access to Eli Lilly’s powerful, still-experimental obesity drug retatrutide through the Food and Drug Administration’s “compassionate use” program—raising immediate questions if that sole patient is President Donald Trump, according to a report by Stat News.

Lilly’s retatrutide is a highly anticipated next-generation obesity drug that targets GIP and glucagon hormones in addition to GLP-1. It is currently in late-stage trials to treat obesity, diabetes, sleep apnea, and other conditions. Data from a Phase 3 trial that Lilly released in May indicates that patients with obesity (but without diabetes) who took the drug for 80 weeks lost 28 percent of their weight, an amount comparable to bariatric surgery.

Millions of Americans with obesity are eager to get the drug, with options being limited so far to enrolling in a clinical trial or trying to obtain it by dodgy methods.

But according to a barebones public notice and Stat’s sources, a single person has been granted early access through the expanded access, aka “compassionate use” pathway, which is typically used to grant access to patients with a “serious or immediately life-threatening disease or condition” and who are not able to enroll in a clinical trial, often because they are too ill.

The access request was first made in April, when the person was 79 years old (Trump turned 80 on June 14). It was made by a senior clinician at the National Institutes of Health named Ranganath Muniyappa, who requested it on behalf of a patient with refractory obesity, obstructive sleep apnea, and pulmonary hypertension, which is high blood pressure in the lungs. Sources told Stat this patient had spent a year on tirzepatide, a drug that targets the GLP-1 and GIP hormones. But the patient had achieved only moderate weight loss on the drug.

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[–] medicsofanarchy@lemmy.world 121 points 4 weeks ago (3 children)

Has he tried copious amounts of injected bleach? Everybody says it works wonders.

[–] themoken@startrek.website 39 points 4 weeks ago (4 children)

There's a new medical procedure that needs to be done only once. Kinetic injection of lead to the brain. So simple it can be self administered, or with the help of a friend in line of sight.

[–] Ceruleum@lemmy.wtf 10 points 4 weeks ago (1 children)

There is no brain there, only poop mush ... You need something stronger.

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[–] phutatorius@lemmy.zip 8 points 4 weeks ago

Eeplacing mayo on burgers with Ivermectin should also help.

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[–] Triumph@fedia.io 77 points 4 weeks ago (2 children)

If it is, pulmonary hypertension will kill him regardless.

[–] AbidanYre@lemmy.world 64 points 4 weeks ago (1 children)
[–] Triumph@fedia.io 37 points 4 weeks ago (1 children)

Not only that, there's a chance we'll get to see it. A sudden physical collapse after which he never leaves the hospital is not unlikely.

[–] turtlesareneat@piefed.ca 10 points 4 weeks ago (2 children)

Buy extra fireworks this year and hold onto them, is all I'm saying.

[–] flightyhobler@lemmy.world 8 points 4 weeks ago* (last edited 4 weeks ago)

Please let go of them once you light them up

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[–] Danarchy@lemmy.nz 70 points 4 weeks ago (1 children)

This is like a yo momma joke. Yr prez is so fat they had to invent a new type of triple-ozempic

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[–] CubitOom@sh.itjust.works 46 points 4 weeks ago

Enigmas never age, have you noticed that?

[–] ExtremeDullard@piefed.social 44 points 4 weeks ago (3 children)

It's probably not him: he's still a lardass.

[–] LastYearsIrritant@sopuli.xyz 57 points 4 weeks ago (1 children)

That's the point, apparently he tried other weight loss drugs and they didn't work. I guess his addiction to McDonald's is stronger than Ozempic.

[–] turtlesareneat@piefed.ca 10 points 4 weeks ago* (last edited 4 weeks ago) (1 children)

Yeah there's a class of folks who have psychological issues around food and so they won't lower their eating when their hunger goes down. Which can be a real fucker since GP1s affect transit time and digestion, this might explain some of his pants pooping.

[–] applebusch@lemmy.blahaj.zone 10 points 4 weeks ago (1 children)

i thought it was from the decades of drug abuse

[–] cmbabul@slrpnk.net 6 points 4 weeks ago

And that he’s fucking 80

[–] Catoblepas@lemmy.blahaj.zone 24 points 4 weeks ago* (last edited 4 weeks ago) (2 children)

I think it was Tracy Morgan who said “I managed to out-eat Ozempic.”

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[–] jballs@sh.itjust.works 43 points 4 weeks ago (3 children)

I've got three family members taking this drug and have both lost a ton of weight. All of them have lost sunstantial amounts of weight. My brother is down 70 pounds.

Ain't no way Trump is taking it. He's still fat as shit.

[–] Quetzalcutlass@lemmy.world 41 points 4 weeks ago (3 children)

The drug works by killing your appetite. Trump's a long-time abuser of amphetamines, which do the same thing. His current obesity means a reduction in appetite did nothing for him, which is probably why the previous anti-obesity drugs also failed.

[–] silicon@lemmy.dbzer0.com 12 points 4 weeks ago (1 children)

As far as we know all he eats is McDonald's so is anyone surprised?

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[–] very_well_lost@lemmy.world 14 points 4 weeks ago (2 children)

Do any of your family members eat McDonald's 3 times a day and only sleep 4 hours a night?

[–] jballs@sh.itjust.works 8 points 4 weeks ago

They used to.

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[–] Formfiller@lemmy.world 31 points 4 weeks ago* (last edited 4 weeks ago) (1 children)
[–] mbp@slrpnk.net 21 points 4 weeks ago
[–] Nastybutler@lemmy.world 26 points 4 weeks ago

The patient's name? John Baron

[–] Kazumara@discuss.tchncs.de 23 points 3 weeks ago (1 children)

It would be extremely funny if he cheated his way to early entry, and then it turns out it isn't safe for old fucks. Like maybe that hasn't been tested since it's still early enough in trials.

[–] prole@lemmy.blahaj.zone 8 points 3 weeks ago* (last edited 3 weeks ago) (1 children)

Until we find out that one of the side effects is violent psychotic dementia

[–] Bluewing@lemmy.world 9 points 3 weeks ago

one of the side effects is violent psychotic dementia

It's not a side effect if the patient already suffers from it....

[–] cenzorrll@piefed.ca 20 points 4 weeks ago (10 children)

Stat reporter Lizzy Lawrence replied, saying, “I asked you, the FDA, and HHS multiple times yesterday whether this application was for the President. No one answered my question directly.” Desai then seemed to confirm that no one had answered the question, calling it an “idiotic question.”

I'm gonna have to agree with Desai here. It's a stupid fucking question. As much as I hate the guy, the only link is a 79 year old. This is national enquirer level of reporting.

[–] BillCheddar@lemmy.world 47 points 4 weeks ago (4 children)

No, the only links are "79 years old," "name not given," and "literally the only person in the country who was approved for this"

That doesn't strike you as "Hmm, maybe we should see if the fat-assed President is once again abusing his office for personal gain?"

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[–] ayyy@sh.itjust.works 6 points 4 weeks ago

Also it’s basic patient privacy. The journalist asking the question surely knows that.

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[–] Zombiepirate@lemmy.world 19 points 4 weeks ago (2 children)

He really could use a retatrutide adjustment.

[–] bobs_monkey@lemmy.zip 9 points 4 weeks ago

Nah, just let the cholesterol do its thing.

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[–] MrSulu@lemmy.ml 18 points 4 weeks ago

Let's pray for non trivial side effects. And I'm not even religious

[–] phoenixz@lemmy.ca 18 points 4 weeks ago

retatrutide

I had to do a double take to make sure it was retardicide... That surely would have gotten rid of the fucker

[–] Rcklsabndn@sh.itjust.works 15 points 3 weeks ago (2 children)

Just imagine how much more disgusting he would look if he lost 50-100 pounds and he was a shambling pile of loose skin.

[–] ccunning@lemmy.world 10 points 3 weeks ago* (last edited 3 weeks ago) (2 children)

Turns out the wicked witch of the west was orange; not green…

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[–] A_Random_Idiot@lemmy.world 6 points 3 weeks ago* (last edited 3 weeks ago)

like one of those zombies that had all the fat and flesh rot out, but their skin.. sun tanned and dried, hangs on, like some kind of moribund hipster fashionista bag.

[–] CADmonkey@lemmy.world 12 points 4 weeks ago (4 children)

Question for someone who knows more about GLP-1 drugs than myself - if you're taking the drug regularly, and you're also self-administering a medicinal Whopper and large fries >1x per day, will you still lose weight? The stuff works but thermodynamics still applies?

[–] manxu@piefed.social 17 points 4 weeks ago (3 children)

The class of drugs works by suppressing appetite. So you just eat less and feel good about it. Which makes restaurant chains very, very nervous.

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[–] YellowParenti@lemmy.wtf 9 points 4 weeks ago (8 children)

Meds kill hunger. You just feel full quickly and for a long time. My coworker brings a normal portion of food to work and only eats maybe half. They told me they don't really feel hungry, but know they have to eat. They eat once a day. I'm pretty sure its just anorexia in a shot. Also this helps with physical hunger, so, if you emotional or stress eat, it won't help as much/lose weight as quickly.

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[–] sloppy_diffuser@sh.itjust.works 7 points 4 weeks ago* (last edited 4 weeks ago) (1 children)

Been on a GLP-1/GIP compounded injection for a year. Lost 90lbs.

I physically have a hard time overeating on fats/protiens. Like I want to vomit. Meat consumption is way down from before.

Simple carbs like starches and sugar I can overinduldge on but seem to get sick faster than before taking the medication.

It mostly helps with food related cravings but its not a silver bullet. I can still fallback to emotional eating under high stress and fluctuate +5 lbs with water retention. Its just much easier to recover.

I lost about 1/3 the weight on my own tracking everything. With the medication it tripled the rate of loss and I didn't need to track anymore. I'm much more able to trust my body and hunger signals developing a healthier relationship with food.

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[–] Warl0k3@lemmy.world 8 points 4 weeks ago

Hmm. Public notice appears to be unavailable...

[–] SocialMediaRefugee@lemmy.world 7 points 3 weeks ago

He needs dementia drugs more.

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