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Pre-birth DNA editing to ensure a healthy and ideal child.
Eugenics is awful. It's horrible. There is no question and there's a million historical and fictional deep dives one can do to objectively prove that it is against any form of morality you could possibly come up with.
But, improving the human experience, ensuring no one is born with a disability, ensuring that everyone has the best possible chance to enjoy and experience life would be amazing. If society could get its collective shit together we could in fact make sure that every person gets the best possible experience of our species. We could pretty much entirely eliminate childhood cancers. We could make super heroes (relative to unmodified humans). We could eliminate genetic defects that have plagued families and entire populations since pre-history.
Is it possible yet? We already have genetic screening which is actively used in many countries. IIRC downs syndrome rates are lower because of it being screened for now. But not everything can be screened for and we don't fully understand all DNA yet.
If you could cure these things with an acceptably low risk of negative effects I am pretty sure people would be in favour of it. The research for that sounds difficult though.
We can do it to living people (Gene Therapy is just editing DNA using an inert virus to deliver the payload and modify gene expressions), and there is a very good chance CRISPR allows it for in utero cells.
If we had zero ethical boards, we'd be at the active experimentation stage to discover what each nucleotide pair precisely does which would involve growing humans directly.
That being said we are doing things that are close to it. For example look up the term organoid. Then Brain organoid. Then realize pretty much every university is growing unique but stunted human brains and experimenting on them; and then realize these organoids dream. Anyway that existential horror aside, this also extends to almost every organ in the human body. We're essentially brute forcing gene expression discovery at the individual component level; if we were to scale that up to a full human (or get much, much faster computers so we could simulate it) we'd have the totality of DNA fully understood.
From there it's trivial to combine our current tech that allows free form editing of DNA with exactly what we would need to change.
Correct me if this is naive, but wouldn't this potentially also reduce the diversity of the gene pool?
Maybe that’s the eugenics issue. Correcting genetic damage might be small and rare. On the other hand if everyone wants a blond blue eyed baby that will grow up to be a 6’2” Adonis, genius, super athlete, then yeah
Only superficially. It's really hard to tell what percentage of our DNA is actually useful, or could be useful under conditions we haven't seen, or is actually a part of any given variation. What we do know, of the number of DNA combinations we have seen if we play out each possible version of those variations there's around 4^2000 variations. Or in other words If a billion people were born every day since the start of the universe, there would not be a single duplicate person. And this is the extreme low end estimate based on limited data sets that generally don't even include people of every major region, much less interesting micro-populations that have been breeding in isolation for a thousand years or more.
Now lets assume we remove all causes of congenital blindness. Generally speaking the number of genes making up most identified causes are less than 20 total. That would (simplified, yell at me later math nerds) knock that number down to around 4^1995.
That would still be more viable combinations than we could possibly run through from now until the heat death of the universe, assuming current population growth rates which we'll have until we invent birthing pods.
In other words we'll probably be fine, but if we need to, and it's allowed to be researched more, we could just simply artifically introduce safe variation. i.e. people giving birth to people they aren't genetically related to anymore.
No. Why? We could literally introduce diversity into the gene pool in a controlled manner.
Who wants their kid to be the one that gets the random mutation injection?
Who said anything about random?
What if you need to be a little crazy to stand out? No one wants a boring a artist, uninspired actor, musician that sounds like all the other ones…
"Oops, we reinvented downs syndrome"
Not adding a full chromosome seems to be easily doable on the basis of our hypothetical situation where we can easily do gene editing.