this post was submitted on 08 Apr 2026
554 points (98.8% liked)

science

26685 readers
592 users here now

A community to post scientific articles, news, and civil discussion.

dart board;; science bs

rule #1: be kind

lemmy.world rules

founded 2 years ago
MODERATORS
top 50 comments
sorted by: hot top controversial new old
[–] chicken@lemmy.dbzer0.com 172 points 2 weeks ago (6 children)

That's great but I've been seeing articles like this for decades so I'll believe it when there's an actual working product you can actually get

[–] But_my_mom_says_im_cool@lemmy.world 50 points 2 weeks ago (6 children)

Right? Im scheduled for a vasectomy in a month, this ain’t stopping me.

[–] absGeekNZ@lemmy.nz 37 points 2 weeks ago (1 children)

One of the best moves I made.

After my partner and I had agreed no more kids....it was down to the doc to get the chop. Very easy, keyhole surgery; I feeling 90% by the next day, 100% the following day. 2.5 days of discomfort for years of stress free times.....worth it!

load more comments (1 replies)
[–] BassTurd@lemmy.world 15 points 2 weeks ago (1 children)

Best $50 I've ever spent. Quick procedure, quick recovery with an excuse to not do anything for a couple days.

[–] StarvingMartist@sh.itjust.works 12 points 2 weeks ago (5 children)

50$???? Where do you live? Can I live there?

[–] ColeSloth@discuss.tchncs.de 13 points 2 weeks ago

That shit is copay. Can't even get a cat neutered for $50.

[–] quick_snail@feddit.nl 12 points 2 weeks ago* (last edited 2 weeks ago) (1 children)

You can also just be brown and walk in front of ICE. They have a history of forced sterilizing

[–] RampantParanoia2365@lemmy.world 9 points 2 weeks ago

Jesus, you're not making that up. I think that may ruin my night.

load more comments (3 replies)
load more comments (4 replies)
[–] elucubra@sopuli.xyz 7 points 2 weeks ago

Scientists at Cornell University

may be

closing in

load more comments (4 replies)
[–] xxce2AAb@feddit.dk 114 points 2 weeks ago

Cool. More options for reproductive agency are always welcome.

[–] HugeNerd@lemmy.ca 104 points 2 weeks ago (8 children)

I just use my personality. Seems simpler.

[–] SkaveRat@discuss.tchncs.de 49 points 2 weeks ago

The new stuff is reversible

[–] JillSteinsPuckeredAnus@lemmy.world 8 points 2 weeks ago (1 children)

I thought it was your looks?

[–] HugeNerd@lemmy.ca 7 points 2 weeks ago (1 children)
load more comments (1 replies)
load more comments (6 replies)
[–] givesomefucks@lemmy.world 38 points 2 weeks ago* (last edited 2 weeks ago) (2 children)

We need this just because Republicans would never tell a straight white man what to do with his body...

And any birth control is better than none, for the periods we can't have all methods.

[–] Droechai@piefed.blahaj.zone 12 points 2 weeks ago

Are the republicans against the draft and the forced labour prison system? Quite a few straight white men there

load more comments (1 replies)
[–] jqubed@lemmy.world 34 points 2 weeks ago (2 children)

Summary:

Scientists at Cornell University may be closing in on the long-sought “holy grail” of male contraception: a safe, reversible, nonhormonal method that completely halts sperm production. In a breakthrough mouse study, researchers used a compound called JQ1 to temporarily shut down meiosis—the critical process that produces sperm—without causing lasting harm. After treatment stopped, sperm production bounced back, fertility returned, and the animals produced healthy offspring.

[–] renzhexiangjiao@piefed.blahaj.zone 26 points 2 weeks ago (3 children)

ah so it's one of those articles whose title is missing "in mice"

[–] jqubed@lemmy.world 7 points 2 weeks ago (1 children)

And I question how viable it is given this:

To achieve this, scientists used JQ1, a small molecule inhibitor originally developed to study cancer and inflammatory diseases. While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1. This allowed researchers to demonstrate, for the first time, that targeting meiosis can safely and reversibly shut down sperm production.

It sounds like calling the treatment “safe” might be a bit of a stretch.

load more comments (1 replies)
[–] kbobabob@lemmy.dbzer0.com 6 points 2 weeks ago (1 children)

Aren't pretty much all of these medical discoveries from mice?

load more comments (1 replies)
load more comments (1 replies)
load more comments (1 replies)
[–] MyTurtleSwimsUpsideDown@fedia.io 29 points 2 weeks ago

While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1. This allowed researchers to demonstrate, for the first time, that targeting meiosis can safely and reversibly shut down sperm production.

If developed for human use, this type of male contraceptive could be delivered as an injection given every three months or possibly as a patch to maintain effectiveness, Cohen said.

[–] daniskarma@lemmy.dbzer0.com 27 points 2 weeks ago

This kind of news is an annual event at this point.

[–] bitjunkie@lemmy.world 25 points 2 weeks ago (1 children)

…in mice, after massive, cancer-causing doses, probably.

I'm tired of hearing about this shit. Put it to market or stop talking about it.

[–] Smoogs@lemmy.world 12 points 2 weeks ago

Yeah just push it out to public. Just like they did with women's contraceptives.

[–] YellowParenti@lemmy.wtf 25 points 2 weeks ago (2 children)

There was this gel that got injected into the tube connecting the balls to the urethra(vas deferens?). It would destroy the sperms as it went through and you where basically sterile. To reverse they injected you again with something and it would become a liquid and you ended up busting it out in a few ejaculations. It's been stuck in early human trials for a decade.

load more comments (1 replies)
[–] HubertManne@piefed.social 18 points 2 weeks ago (8 children)

To achieve this, scientists used JQ1, a small molecule inhibitor originally developed to study cancer and inflammatory diseases. While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1.

[–] kungen@feddit.nu 20 points 2 weeks ago (3 children)

So the substance isn't a possible treatment for cancer because of neurological side effects... and their next step is "let's sell it to guys who aren't able to use condoms"?

[–] monotremata@lemmy.ca 11 points 2 weeks ago

I think the idea is that this particular drug isn't suitable as birth control, but having identified that this mechanism/biological pathway can work for birth control, they can look for a less toxic compound to achieve the same effect.

[–] HubertManne@piefed.social 7 points 2 weeks ago

sounds that way to me. I think the thing like always is the title. its something they noticed and now a track to find something that does a similar type of mechanism without the bad side effects.

load more comments (1 replies)
load more comments (7 replies)
[–] caboose2006@lemmy.world 8 points 2 weeks ago (3 children)

Didn't they figure that out with Vasalgel?

load more comments (3 replies)
[–] HubertManne@piefed.social 7 points 2 weeks ago
[–] AmidFuror@fedia.io 7 points 2 weeks ago (3 children)

Now I'm curious if irreversible methods are considered "birth control." It seems redundant to write "reversible birth control," but maybe I've been using too narrow a definition. I consider IUDs to be birth control, but not vasectomies. The distinction is the level of effort required to reverse.

If completely irreversible, is that not considered sterilization?

[–] Omgpwnies@lemmy.world 8 points 2 weeks ago (3 children)

I had a vasectomy because I don't want any more children, I think that counts as birth control. Anything that prevents conception is contraceptive in nature.

load more comments (3 replies)
load more comments (1 replies)
load more comments
view more: next ›